Workshop #2: SAMPREP (Sample Attributes for Multiple-techniques and Principal Requirements for Experiments in Pan-structural biology) Workshop

	SPONSORED BY:

The routine use of multi-technique approaches to answer the most complex and challenging questions in structural biology has dramatically increased in recent years. We believe the 2023 meeting in Baltimore is an excellent destination for bringing together Cryo-EM, MX and SAS experts to prepare students and investigators new to the methods for the successful application of these techniques. We are particularly excited to offer this workshop in conjunction with the stated goal of the 2023 meeting organizing committee to attract early career scientists via a more education focused meeting program. This one-day workshop will provide introduction to both the theory of the methods and best practices common to the field with a focus on the importance of the quality of samples. In addition to synchrotron sources, this workshop will devote content to laboratory best practices in the preparation of samples and their manipulation at the home lab and their transportation to Cryo-EM centers and synchrotrons. In contrast to the more intensive courses at synchrotrons around the world that extend across several days, but usually cover only one technique, this single day of carefully constructed lectures and tutorials is an introduction aimed at improving the chances for success in preliminary experiments. The material is appropriate for investigators new to the field, or for those with experience in one structural biology technique to gain the knowledge they need to pursue others, and elevate the standards for published data and peer-review. The workshop format will include lectures and a selection of hands-on practical exercises. Throughout the workshop the emphasis will be on practical application: knowing how to judge sample quality, how to troubleshoot during sample preparation, and the expectations for a successful experiment and acceptable publication.